The Forgotten—and Incredibly Important—History of the Abortion Pill

Mifepristone took longer to get approved than most drugs—but not because it was unsafe.

Nina Martin, Mother Jones
Feb 7, 2025

At his Senate confirmation hearings to head the Trump administration’s Department of Health and Human Services, Robert F. Kennedy Jr. surprised no one by admitting that he planned to order a new review of the safety of abortion pills. While Kennedy claimed that President Donald Trump has not taken a position—yet—on medication abortion, “he’s made it clear to me that he wants me to look at the safety issues,” Kennedy said. “And I’ll ask [agencies] to do that.”

This, of course, is exactly what anti-abortion groups have been pushing for. Since 2022, when the US Supreme Court overturned the constitutional right to abortion in the Dobbs v. Jackson Women’s Health Organization decision, abortion opponents have been ramping up unfounded claims that mifepristone and misoprostol are dangerous. Their efforts have included a flurry of letters to the new administration, explicit directives in the far right’s Project 2025 blueprint for the second Trump term, and a barrage of ever-more-extreme lawsuits and state bills.

Continued: https://www.motherjones.com/politics/2025/02/abortion-pill-forgotten-history-attacks-mifepristone-ru486-anti-abortion-extremists-new-book/

07.02.2025

Commentary

abortion pills

Abortion Pills: US History and Politics

Alliance for Hippocratic Medicine

Dobbs v. Jackson Women's Health Organization

Feminist Majority Foundation

Food and Drug Administration

manual vacuum aspiration

Reproductive Health Technologies Project

Risk Evaluation and Mitigation Strategies

Roussel-Uclaf

RU-486

Searle

Shanghai Hualian Pharmaceutical Company

shield laws

telehealth abortion

telehealth clinics

telemedicine abortion

USA – The Anti-Abortion Movement’s Biggest Fear

BY DAHLIA LITHWICK
MARCH 25, 2024

On Tuesday, the Supreme Court is scheduled to hear oral arguments in FDA v. Alliance for Hippocratic Medicine, a case that could determine national access to mifepristone, one of two pills used as part of medication abortion. In this week’s episode of Amicus, Dahlia Lithwick spoke with Carrie N. Baker, whose book, History and Politics of Abortion Pills in the United States, is being published by Amherst College Press this year.

Lithwick and Baker discussed the anti-abortion movement’s decadeslong efforts to target the abortion pill, how those efforts hampered FDA approval of the medication in the first place, and how having easier access to reproductive care through a pill that can be sent in the mail and taken at home fundamentally threatens the strategy of those seeking to dismantle abortion rights in this country. The following transcript has been edited for length and clarity.

Continued: https://slate.com/news-and-politics/2024/03/abortion-pill-supreme-court-preview-mifepristone-history.html

Abortion pill mifepristone: An explainer and research roundup about its history, safety and future

Amid pending court cases and ballot initiatives, journalistic coverage of medication abortion has never been more crucial. This piece aims to help inform the narrative with scientific evidence.

by Naseem S. Miller
November 1, 2023

Access to mifepristone, a medication that’s used for the safe termination of early pregnancy, hangs in the balance while the U.S. Supreme Court decides whether to take up a case that could determine the legal future of the abortion medication.

In August, the 5th U.S. Circuit Court of Appeals ruled that mifepristone should not be prescribed past the seventh week of pregnancy, prescribed via telemedicine, or shipped to patients through the mail. In September, the Justice Department asked the Supreme Court to consider a challenge to that ruling.

Continued: https://journalistsresource.org/health/mifepristone-research-roundup/

How mifepristone became a target of the US anti-abortion movement

The abortion pill, first invented in 1980 in France, was slow to be accepted in the US. Now, it’s at the center of a major court fight

by Poppy Noor
Wed 17 May 2023

The future of mifepristone, a crucial abortion drug, is currently in question as US courts consider a challenge brought by anti-abortion groups. Considering medication is the most common US abortion method, it is the most significant reproductive rights case to make its way through the courts since Roe v Wade was overturned in 2022.

The groups suing the Food and Drug Administration over its approval of the drug claim that the drug poses a threat to women and girls – contrary to scientific consensus – and should never have been approved by the FDA more than two decades ago. The FDA vehemently stands by its approval of the pill, with the Biden administration emphasizing the agency’s rigorous safety reviews of the drug.

Continued: https://www.theguardian.com/world/2023/may/16/how-mifepristone-became-a-target-of-the-us-anti-abortion-movement

17.05.2023

Commentary

abortion pills

Claude Evin

Food and Drug Administration

The long and winding history of the war on abortion drugs

Along with the stethoscope and camembert cheese, mifepristone may be one of France’s greatest inventions. It’s one of two drugs taken for medical abortions, along with misoprostol, and has been making headlines in the US, where a Texas judge issued a ruling to ban it nationwide. FRANCE 24 takes a look at the history of these two drugs.

26/04/2023
by Lara BULLENS

Two separate rulings filed one after another in quick succession on April 7 had US abortion providers holding their breath. The first, issued by Trump-appointed federal judge Matthew Kacsmaryk, ordered a hold on mifepristone, one of two drugs taken for medical abortions. The second, issued by Obama-appointed federal judge Thomas O. Rice, came less than an hour later. His ruling ordered the exact opposite.

Continued: https://www.france24.com/en/health/20230426-the-long-and-winding-history-of-the-war-on-abortion-drugs

The Abortion Pill’s Secret Money Men

The untold story of the private equity investors behind Mifeprex—and their escalating legal battle to cash in post-Dobbs.

HANNAH LEVINTOVA
Mother Jones, MARCH+APRIL 2023 ISSUE

In 1993, a group of activists rented a warehouse in suburban Westchester County, New York. It was smaller than they’d hoped and had limited ventilation, but the two other locations they’d tried to rent belonged to universities and required jumping through too many bureaucratic hoops—the exact sort of paper trail this group was trying to avoid.

Led by renowned pro-choice activist Lawrence Lader, their goal was to replicate RU-486, the revolutionary abortion pill developed in the 1980s by French manufacturer Roussel-Uclaf—which was unwilling to navigate American abortion politics to bring the pill stateside.

Continued: https://www.motherjones.com/politics/2023/01/abortion-pill-mifepristone-mifeprex-roe-dobbs-private-equity/

The Father of the Abortion Pill

The 96-year-old scientist who came up with an idea for an “unpregnancy pill” decades ago has led an eventful life, from his teenage days in the French Resistance to his friendships with famous artists.

By Pam Belluck
Jan. 17, 2023

When the idea struck him, nearly 50 years ago, Dr. Étienne-Émile Baulieu believed it could be revolutionary. Creating a pill that could abort a pregnancy would transform reproductive health care, he thought, allowing women to avoid surgery, act earlier and carry out their decisions in private.

“When science meets women’s cause, it is irresistible,” Dr. Baulieu, 96, a French endocrinologist and biochemist often called the father of the abortion pill, said on a recent Sunday afternoon in his apartment in a century-old building a short walk from the Eiffel Tower.

Continued: https://www.nytimes.com/2023/01/17/health/abortion-pill-inventor.html

21 Years After FDA Approval, Abortion Pill Is More Critical Than Ever

With the Supreme Court poised to overturn Roe v. Wade, the fight for access to the abortion pill has become a matter of life and death.

9/27/2021
by CARRIE N. BAKER

Twenty-one years ago, the U.S. Food and Drug Administration (FDA) approved the abortion pill mifepristone for distribution in the United States. As states are now passing laws to ban abortion and the U.S. Supreme Court is poised to overturn Roe v. Wade, the abortion pill is what will make a post-Roe world very different from the pre-Roe world, when thousands of women died each year from illegal abortions, and many more were left permanently harmed by unsafe and illegal abortions.

Abortion pills are safe and effective, widely accessible online and easy to use. A grassroots movement led by the organization Plan C is now working to ensure that women across the country know how to get abortion pills and how to use them.

Continued: https://msmagazine.com/2021/09/27/fda-approval-abortion-pill-anniversary-medication-abortion-biden-texas-ban/

USA – Abortion Pill Effective for Treating Fibroids, But Anti-Abortion Politics Stymie Access

7/26/2021
by CARRIE N. BAKER, Ms. Magazine

In 2000, the U.S. Federal Drug Administration (FDA) approved mifepristone for abortion during the first seven weeks of pregnancy, later extending allowable use to ten weeks in 2016. While widely known as an abortion pill, mifepristone is very effective for treating fibroids and may also be effective for treating endometriosis and depression.

Yet the drug is not available to use for these serious conditions because the FDA tightly restricts the medication due to intense anti-abortion pressure. The politicization around mifepristone has made research on its usefulness in treating these conditions difficult to conduct, preventing its development for treatments that could significantly enhance women’s health.

Continued: https://msmagazine.com/2021/07/26/mifepristone-abortion-pill-fibroids-endometriosis-depression-fda-rems-biden/